Table 3.

Five-year probabilities of event-free and overall survival by age and donor type

Donor typeEvent-free survival (95% CI), %Overall survival (95% CI), %
Age, ≤6 y
 HLA-matched relative88 (84-91)92 (89-95)
 HLA-mismatched relative73 (59-86)75 (61-87)
 HLA-matched unrelated89 (83-93)93 (88-96)
 HLA-mismatched unrelated83 (73-91)89 (81-96)
Age, 7-15 y
 HLA-matched relative80 (75-85)84 (79-88)
 HLA-mismatched relative56 (39-73)62 (44-78)
 HLA-matched unrelated89 (82-95)91 (83-97)
 HLA-mismatched unrelated71 (54-85)79 (63-91)
  • Patients aged 16-25 years: N = 24 patients who received HLA-matched related donor transplantation with event-free survival of 58% (14 of 24) and overall survival of 63% (15 of 24). N = 4 patients received HLA-mismatched related donor transplantation and only 2 patients are alive. N = 4 patients received HLA-matched unrelated donor transplantation and all patients are alive. N = 1 patient received HLA-mismatched unrelated donor transplantation and is death.