Table 1.

Patient and transplant characteristics

No. (%)
Age at transplantation, y
 ≤6638 (57)
 7-15439 (40)
 16-2533 (3)
Sex
 Male/female696 (63)/414 (37)
Red blood cell transfusions prior to transplantation
 <2040 (4)
 20-50304 (27)
 >50634 (57)
 Not reported132 (12)
Iron chelation
 Adequate117 (11)
 Inadequate981 (88)
 Not reported12 (1)
Hepatomegaly
 Absent280 (25)
 Present806 (73)
 Not reported24 (2)
Donor type
 HLA-matched relative677 (61)
 HLA-mismatched relative78 (7)
 HLA-matched unrelated252 (23)
 HLA-mismatched unrelated103 (9)
Graft type
 Bone marrow321 (29)
 Peripheral blood682 (61)
 Cord blood107 (10)
In vivo T-cell depletion
 Yes/none827 (75)/283 (25)
Conditioning regimen
 BU/Cy/TT/FLU376 (34)
 BU/Cy/FLU259 (23)
 BU/Cy249 (22)
 Treosulfan/TT/FLU169 (15)
 BU or melphalan ± TT ± FLU57 (5)
GVHD prophylaxis
 Calcineurin inhibitor/methotrexate/mycophenolate187 (17)
 Calcineurin inhibitor/methotrexate446 (40)
 Calcineurin inhibitor/mycophenolate350 (32)
 Calcineurin inhibitor alone31 (3)
 Posttransplant Cy/cyclosporine/mycophenolate96 (9)