Time point | ORR (N = 25), n (%) | 95% Clopper-Pearson CI |
---|---|---|

Day 42 | 20 (80) | 0.59-0.93 |

Day 100^{*} | 19 (76) | 0.55-0.91 |

Day 180 | 16 (64) | 0.43-0.82 |

Day 270 | 13 (52) | 0.31-0.72 |

Year 1^{†} | 11 (44) | 0.24-0.65 |

ORR is defined as the proportion of patients who have a positive response by IMWG 2011 criteria (sCR, CR, VGPR, PR) relative to the total number of patients in the population.

CR, complete response; PR, partial response; sCR, stringent complete response; VGPR, very good partial response.

↵* Day 100 responders (n = 19): 1 sCR, 12 VGPR, and 6 PR.

↵† Year 1 responders (n = 11): 1 sCR, 1 CR, 8 VGPR, and 1 PR.