Table 1.

Hip arthroplasty perioperative hemostasis regimen with emicizumab

TimeSingle doseInterval, h
36812
PreoperativeEmicizumab 1.5 mg/kg
PreoperativerFVIIa 180 μg/kg
POD 0rFVIIa 90 μg/kg
POD 1rFVIIa 90 μg/kg
POD 2rFVIIa 90 μg/kg
POD 3rFVIIa 90 μg/kg
POD 4rFVIIa 90 μg/kg
POD 5rFVIIa 90 μg/kg
POD 6rFVIIa 90 μg/kg
POD 7Emicizumab 1.5 mg/kgrFVIIa 90 μg/kg
POD 8rFVIIa 90 μg/kg
POD 9rFVIIa 90 μg/kg
POD 10rFVIIa 90 μg/kg
POD 11rFVIIa 90 μg/kg
POD 12rFVIIa 90 μg/kg
POD 13rFVIIa 90 μg/kg
POD 14Emicizumab 1.5 mg/kgrFVIIa 90 μg/kg
  • POD, postoperative day.