Table 3.

Distribution of events in the randomized patients with and without DS

Event typesPO MTXIV MTXSDIDDI
DS (n = 44)Non-DS (n = 992)DS (n = 31)Non-DS (n = 1011)DS (n = 42)Non-DS (n = 993)DS (n = 33)Non-DS (n = 1010)
Event-free36876299243789528905
iBM54560344261
iCNS27112216
BM + CNS125107
BM + testicular14113
BM + other14311
CNS + other1111
Testicular9164
Other relapse5142
Second malignant neoplasm182146
Death as first event15121314
Total events81162875985105
  • —, not calculated; iBM, isolated BM relapse; iCNS, isolated CNS relapse.