Table 2.

P50 and n50 values for HbF treated with phthalide and 2,3-BPG under various treatment conditions

No phthalidePhthalide
0.6 mM1.2 mM4.0 mM
P50n50P50n50P50n50P50n50
z-Butylidenephthalide
 No 2,3-BPG14.602.5915.872.6216.682.6217.062.56
 2,3-BPG
  0.60 mM14.912.5916.112.6516.352.717.862.56
  1.2 mM15.122.5816.422.6616.372.6818.112.52
  2.5 mM15.922.5916.622.6617.42.7118.632.52
  4.0 mM16.562.5917.372.6317.292.6819.542.54
z-Ligustilide
 No 2,3-BPG14.602.5915.982.5416.162.5416.692.51
 2,3-BPG
  0.60 mM14.912.5916.032.6416.342.716.792.66
  1.2 mM15.122.5816.482.6516.582.716.842.67
  2.5 mM15.922.5917.012.6717.032.6817.932.69
  4.0 mM16.562.5917.392.6418.092.7118.742.7
  • P50 units are mm Hg.