Table 1.

Patient characteristics

CharacteristicNo. (%)
Total number of patients17 980
Patient age at transplantation (range), y34 (0-76)
 <153918 (22)
 15-293922 (22)
 30-392911 (16)
 40-493098 (17)
 ≥504131 (23)
Patient sex
 Male10 248 (57)
 Female7732 (43)
Diagnosis
 AML5789 (32)
 ALL4077 (23)
 Lymphoma/CLL1782 (10)
 CML1678 (9)
 MDS1663 (9)
 ATL440 (2)
 MPN322 (2)
 Plasma cell neoplasms243 (1)
 Aplastic anemia1322 (7)
 Immunodeficiency306 (2)
 Bone marrow failure182 (1)
 Inborn metabolic disorders176 (1)
Disease risk
 Standard10 547 (59)
 High5447 (30)
 Nonmalignant1986 (11)
Conditioning
 Myeloablative11 198 (62)
 Reduced intensity5184 (29)
 Unknown intensity1598 (9)
Donor type
 Related bone marrow5061 (28)
 Related mobilized blood cells2509 (14)
 Unrelated bone marrow7241 (40)
 Unrelated mobilized blood cells18 (<1)
 Cord blood2845 (16)
 Haploidentical related306 (2)
HLA matching*
 Match10 909 (74)
 Mismatch3920 (26)
Year of transplantation
 1974-19993613 (20)
 2000-20055260 (29)
 2006-20139107 (51)
Maximum grade of acute GVHD
 Grade 0-I11 903 (66)
 Grade II4528 (25)
 Grade III-IV1549 (9)
Chronic GVHD before 2 y
 None10 228 (57)
 Limited3419 (19)
 Extensive4333 (24)
  • AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; ATL, adult T-cell leukemia/lymphoma; CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm.

  • * Cord blood and haploidentical transplantation are excluded.