Table 1.

Bleeding in HA controls and AAV-rat FVIIa-infused HA rats expressing <708 ng/ml (HA-AAV <708) or ≥708 ng/ml (HA-AAV ≥708) of rat FVIIa

HA controls, n (%)HA-AAV <708, n (%)HA-AAV ≥708, n (%)*
Animals with bleeds10 (91)15 (83)5 (33)
Animals with no bleeds1 (9)3 (17)10 (67)
Number of animals11 (100)18 (100)15 (100)
  • * P < .05 vs HA controls (Fisher's exact test).

  • P < .05 vs HA-AAV <708 (Fisher's exact test).