Table 2.

The number of bleeds classified by type that were observed in the HA controls and AAV-rat FVIIa-infused HA rats expressing <708 ng/mL (HA-AAV <708) or ≥708 ng/mL (HA-AAV ≥708) of rat FVIIa

Bleed typeHA controls, n (%)HA-AAV <708, n (%)HA-AAV ≥708, n (%)
Rear limbs10 (50)10 (37)4 (44.5)
Front limbs5 (25)13 (48)4 (44.5)
Lacerations2 (10)1 (4)0 (0)
Eyes2 (10)2 (7)0 (0)
Other1 (5)1 (4)1 (11)
Total bleeds20 (100)27 (100)9 (100)
  • There was no statistically significant difference in the location distribution among the 3 groups (Fisher's exact test, P = .933)