Table 3.

Multivariate analysis of risk factors for GRFS

VariablesCBMRD1-MMRDMUD1-MMUD
HR (95% CI)PHR (95% CI)PHR (95% CI)PHR (95% CI)PHR (95% CI)P
Use of ATG*
 ATG(−)11111
 ATG(+)1.458 (0.995-1.979).0530.990 (0.530-1.851).950.915 (0.634-1.322).641.360 (0.870-2.125).180.515 (0.361-0.734)<.01
Age at HSCT, y
 0-201111
 21-401.373 (1.114-1.693)<.01
 41-601.481 (1.225-1.790)<.011.398 (1.132-1.727)<.011.677 (1.318-2.135)<.01
 ≥611.906 (1.558-2.331)<.011.690 (1.284-2.224)<.011.927 (1.121-3.313)01.899 (1.417-2.545)<.01
Disease status at HSCT
 CR111
 ≥CR21.174 (1.002-1.374).051.265 (1.051-1.524).01
Donor source
 BM1<.01
 PB1.339 (1.170-1.532)
ECOG-PS
 0-21
 3-41.820 (1.338-2.476)<.01
HLA disparity
 Match1
 Mismatch1.233 (1.003-1.515).046
Sex
 Male11
 Female0.832 (0.731-0.948)<.010.777 (0.678-0.889)<.01
  • —, HR was not shown because the data was not significant.

  • * Use of ATG was presented as variables of interest.

  • HLA 1- or 2-antigen–mismatched CB.