Table 2.

Multivariate analysis of the clinical impact of ATG in each donor type

CBMRD1-MMRDMUD1-MMUD
nHR (95% CI)PnHR (95% CI)PnHR (95% CI)PnHR (95% CI)PnHR (95% CI)P
Neutrophil engraftment
 ATG(−)18621175411531170918601
 ATG(+)531.213 (0.833-1.765).31180.919 (0.659-1.281).62721.083 (0.802-1.462).60330.946 (0.671-1.332).751031.115 (0.920-1.351).27
Platelet engraftment
 ATG(−)18621175411531170918601
 ATG(+)530.987 (0.699-1.393).94180.882 (0.502-1.549).66721.087 (0.809-1.460).58330.893 (0.570-1.400).621030.898 (0.716-1.126).35
Grades II to IV aGVHD
 ATG(−)18621175411531170918601
 ATG(+)530.900 (0.543-1.494).68180.163 (0.022-1.205).08720.552 (0.352-0.863)<.01330.712 (0.368-1.378).311030.576 (0.399-0.832)<.01
Extensive cGVHD
 ATG(−)16271168311441159117741
 ATG(+)410.455 (0.112-1.852).27160.210 (0.029-1.502).12620.517 (0.262-1.022).06291.326 (0.589-2.983).50930.460 (0.244-0.869).02
NRM
 ATG(−)18621175411531170918601
 ATG(+)531.608 (1.048-2.468).03181.161 (0.271-4.966).84720.764 (0.383-1.525).45331.475 (0.702-3.101).301030.545 (0.315-0.944).03
RI
 ATG(−)18621175411531170918601
 ATG(+)531.023 (0.527-1.988).95182.026 (0.968-4.242).06721.216 (0.579-2.555).61331.206 (0.572-2.545).621030.773 (0.410-1.459).43
OS
 ATG(−)18621175411531170918601
 ATG(+)531.403 (0.991-2.145).054182.092 (1.033-4.237).04720.867 (0.526-1.430).58331.358 (0.763-2.417).301030.673 (0.438-1.033).07
  • 95% CI, 95% confidence interval.