Table 2.

Adverse events assessed as at least possibly related to bortezomib

CTC system organ classCTC adverse event termCTC adverse event gradeAll
1234
NNNNN
Blood and lymphatic system disordersAnemia059014
Febrile neutropenia00202
Eye disordersBlurred vision10001
Gastrointestinal disordersAbdominal pain00101
Constipation11002
Diarrhea11204
Mucositis oral11002
Nausea40004
Vomiting30003
General disorders and administration site conditionsFatigue40105
Fever10001
Injection site reaction10001
Pain10001
Infections and infestationsMucosal infection10001
InvestigationsAlkaline phosphatase increase20002
Lymphocyte count decreased10326
Neutrophil count decreased022812
Platelet count decreased014712
White blood cell decreased021710
Metabolism and nutrition disordersAnorexia11002
Hypokalemia00101
Hypomagnesemia10001
Hyponatremia10001
Hypophosphatemia01405
Nervous system disordersDysgeusia10001
Headache21003
Neuralgia10102
Paresthesia10001
Peripheral sensory neuropathy20002
Seizure00101
Syncope00101
Psychiatric disordersInsomnia01001
Respiratory disordersCough10001
Skin and subcutaneous tissue disordersAlopecia01001
Vascular disordersHypotension00202
  • CTC, Common Toxicity Criteria.