Table 5.

Multivariable associations of patient and treatment characteristics with OS and LSS among AYA with ALL treated in an adult setting, ages 15-39 y, 2009-2014, California

OSLSS
HR (95% CI)PHR (95% CI)P
Sex.27.59
 Female0.82 (0.58-1.16)0.90 (0.62-1.31)
 MaleRef.Ref.
Race/ethnicity.60.04
 Asian/PI1.39 (0.73-2.62)1.73 (0.85-3.51)
 Hispanic1.82 (1.22-2.74)2.10 (1.31-3.35)
 NH African American2.04 (0.78-5.36)2.19 (0.74-6.51)
 Other/ unknown2.02 (0.48-8.56)2.80 (0.64-12.17)
 NH whiteRef.Ref.
Front-line ALL regimen.83.21
 Pediatric1.05 (0.70-1.57)1.33 (0.85-2.08)
 AdultRef.Ref.
Induction facility is COG center or NCI CC0.280.10
 Yes0.81 (0.56-1.19)0.70 (0.46-1.07)
 NoRef.Ref.
  • Final model is stratified on age and includes sex, type of induction, NCI/COG CC status, and all variables significant at the P < .10 level.