Table 3.

Multivariable associations of patient and treatment characteristics with OS and LSS among AYA with ALL, ages 15-39 y, 2004-2014, California

OSLSS
HR (95% CI)PHR (95% CI)P
Sex.27.64
 Female0.91 (0.76-1.08)0.96 (0.79-1.16)
 MaleRef.Ref.
Age at diagnosis, y.07.38
 15-180.75 (0.51-1.10)0.86 (0.58-1.29)
 19-240.83 (0.63-1.08)0.85 (0.64-1.14)
 25-291.13 (0.84-1.51)1.08 (0.79-1.49)
 30-341.08 (0.81-1.44)1.09 (0.80-1.48)
 35-39Ref.Ref.
Race/ethnicity<.001<.001
 Asian/PI1.1 (0.79-1.08)1.14 (0.76-1.71)
 Hispanic1.64 (1.30-2.06)1.76 (1.39-2.24)
 NH African American2.07 (1.28-3.35)2.01 (1.19-3.39)
 Other/ unknown1.97 (0.72-5.40)2.41 (0.88-6.61)
 NH whiteRef.Ref.
Treatment setting.001<.001
 Pediatric0.53 (0.37-0.76)0.51 (0.35-0.74)
 AdultRef.Ref.
Induction facility is COG center or NCI CC.019.026
 Yes0.80 (0.66-0.96)0.80 (0.65-0.97)
 NoRef.Ref.
  • Final model includes age, sex, and all variables significant at the P < .10 level.

  • Ref, reference.