Table 1.

TRAF3 deficiency in human DLBCL samples

ParameterTotal number of samplesTRAF3 deficient, n (%)
Exome sequencing (of 51 samples tested)516 (11.7) by exome sequencing
TRAF3 protein staining (277 samples tested)27795 (34.3) by immunohistochemistry
LMP1 protein positive (of 277 tested)5030 (60.0) by immunohistochemistry
LMP1 protein negative (of 277 tested)22764 (28.1) by immunohistochemistry
  • LMP1-positive and -negative samples differ significantly in their percentage of TRAF3high and TRAF3low staining, as determined by the Fisher's exact test (P < .0001).