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Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL

Lina Hamadeh, Amir Enshaei, Claire Schwab, Cristina N. Alonso, Andishe Attarbaschi, Gisela Barbany, Monique L. den Boer, Judith M. Boer, Marcin Braun, Luciano Dalla Pozza, Sarah Elitzur, Mariana Emerenciano, Larisa Fechina, Maria Sara Felice, Eva Fronkova, Irén Haltrich, Mats M. Heyman, Keizo Horibe, Toshihiko Imamura, Marta Jeison, Gábor Kovács, Roland P. Kuiper, Wojciech Mlynarski, Karin Nebral, Ingegerd Ivanov Öfverholm, Agata Pastorczak, Rob Pieters, Henriett Piko, Maria S. Pombo-de-Oliveira, Patricia Rubio, Sabine Strehl, Jan Stary, Rosemary Sutton, Jan Trka, Grigory Tsaur, Nicola Venn, Ajay Vora, Mio Yano, Christine J. Harrison and Anthony V. Moorman on behalf of the International BFM Study Group

Article Information

Citation 
vol. 3 no. 2 148-157
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted September 5, 2018
  • Accepted December 6, 2018
  • Published online January 16, 2019.


Contributors 
  • Lina Hamadeh, 1Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom;
  • Amir Enshaei, 1Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom;
  • Claire Schwab, 1Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom;
  • Cristina N. Alonso, 2Hematology-Oncology Department, Hospital de Pediatría “Prof. Dr. J. P. Garrahan,” Buenos Aires, Argentina;
  • Andishe Attarbaschi, 3Department of Pediatric Hematology and Oncology, St. Anna Children’s Hospital, Medical University of Vienna, Vienna, Austria;
  • Gisela Barbany, 4Department of Molecular Medicine and Surgery, Clinical Genetics Section, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;
  • Monique L. den Boer, 5Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;
  • Judith M. Boer, 5Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;
  • Marcin Braun, 6Department of Pathology, Medical University of Lodz, Lodz, Poland;
  • Luciano Dalla Pozza, 7Cancer Center for Children, Sydney Childrens Hospital Network, Westmead, NSW, Australia;
  • Sarah Elitzur, 8Pediatric Hematology Oncology, Schneider Children’s Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;
  • Mariana Emerenciano, 9Division of Clinical Research, Research Centre, Instituto Nacional de Câncer, Rio de Janeiro, Brazil;
  • Larisa Fechina, 10Regional Children’s Hospital 1, Ekaterinburg, Russia;11Research Institute of Medical Cell Technologies, Ekaterinburg, Russia;
  • Maria Sara Felice, 2Hematology-Oncology Department, Hospital de Pediatría “Prof. Dr. J. P. Garrahan,” Buenos Aires, Argentina;
  • Eva Fronkova, 12Childhood Leukaemia Investigation, Prague, Czech Republic;13Department of Paediatric Haematology/Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic;
  • Irén Haltrich, 142nd Department of Paediatrics, Semmelweis University, Budapest, Hungary;
  • Mats M. Heyman, 15Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden;
  • Keizo Horibe, 16Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan;
  • Toshihiko Imamura, 17Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan;
  • Marta Jeison, 18Cancer Cytogenetic Laboratory, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel;
  • Gábor Kovács, 142nd Department of Paediatrics, Semmelweis University, Budapest, Hungary;
  • Roland P. Kuiper, 5Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;
  • Wojciech Mlynarski, 19Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland;
  • Karin Nebral, 20Children’s Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria;
  • Ingegerd Ivanov Öfverholm, 4Department of Molecular Medicine and Surgery, Clinical Genetics Section, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;
  • Agata Pastorczak, 19Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland;
  • Rob Pieters, 5Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;21Dutch Childhood Oncology Group, Utrecht, The Netherlands;
  • Henriett Piko, 221st Department of Medicine, Semmelweis University, Budapest, Hungary;
  • Maria S. Pombo-de-Oliveira, 23Pediatric Haematology-Oncology Program, Research Centre, Instituto Nacional de Câncer, Rio de Janeiro, Brazil;
  • Patricia Rubio, 2Hematology-Oncology Department, Hospital de Pediatría “Prof. Dr. J. P. Garrahan,” Buenos Aires, Argentina;
  • Sabine Strehl, 20Children’s Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria;
  • Jan Stary, 13Department of Paediatric Haematology/Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic;
  • Rosemary Sutton, 24Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; and
  • Jan Trka, 12Childhood Leukaemia Investigation, Prague, Czech Republic;13Department of Paediatric Haematology/Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic;
  • Grigory Tsaur, 10Regional Children’s Hospital 1, Ekaterinburg, Russia;11Research Institute of Medical Cell Technologies, Ekaterinburg, Russia;
  • Nicola Venn, 24Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; and
  • Ajay Vora, 25Department of Haematology, Great Ormond Street Hospital, London, United Kingdom
  • Mio Yano, 17Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan;
  • Christine J. Harrison, 1Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom;
  • Anthony V. Moorman, 1Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom;

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