Advertisement

Leukocytosis and thrombosis in essential thrombocythemia and polycythemia vera: a systematic review and meta-analysis

Alessandra Carobbio, Alberto Ferrari, Arianna Masciulli, Arianna Ghirardi, Giovanni Barosi and Tiziano Barbui

Data supplements

Article Figures & Data

Figures

  • Figure 1.

    PRISMA flow diagram of study selection process.

  • Figure 2.

    Forest plot of the random effects meta-analysis assessing the pooled RR of leukocytosis on the primary outcome (thrombosis). Squares and horizontal lines represent the point estimates and associated 95% CIs. The diamond represents the pooled RR, with the center representing the point estimate and the width representing the associated 95% CIs.

  • Figure 3.

    Forest plot of the subgroup analysis on the primary outcome according to MPN diagnosis. Results are presented in the subgroups of patients with ET or PV. Squares and horizontal lines represent the point estimates and associated 95% CIs. The diamonds represent the pooled RRs, with the center representing the point estimate and the width representing the associated 95% CIs.

  • Figure 4.

    Forest plot of the subgroup analysis on primary outcome according to type of thrombosis. Results are presented in the subgroups of patients with arterial or venous events. Squares and horizontal lines represent the point estimates and associated 95% CIs. The diamonds represent the pooled RRs, with the center representing the point estimate and the width representing the associated 95% CIs.

  • Figure 5.

    Forest plot of the random effects meta-analysis assessing the pooled RRs of leukocytosis on a secondary outcome (death). Squares and horizontal lines represent the point estimates and associated 95% CIs. The diamond represents the pooled RR, with the center representing the point estimate and the width representing the associated 95% CIs.