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T-cell assays confirm immunogenicity of tungsten-induced erythropoietin aggregates associated with pure red cell aplasia

Tina Rubic-Schneider, Masataka Kuwana, Brigitte Christen, Manuela Aßenmacher, Otmar Hainzl, Frank Zimmermann, Robert Fischer, Vera Koppenburg, Salah-Dine Chibout, Timothy M. Wright, Andreas Seidl and Michael Kammüller

Article Information

Citation 
vol. 1 no. 6 367-379
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted October 3, 2016
  • Accepted January 6, 2017
  • Published online February 9, 2017.


Contributors 
  • Tina Rubic-Schneider, 1Discovery and Investigative Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland;
  • Masataka Kuwana, 2Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan;
  • Brigitte Christen, 1Discovery and Investigative Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland;
  • Manuela Aßenmacher, 3Technical Development Biosimilars, Novartis Biologics Technical Development and Manufacturing, Oberhaching, Germany; and
  • Otmar Hainzl, 3Technical Development Biosimilars, Novartis Biologics Technical Development and Manufacturing, Oberhaching, Germany; and
  • Frank Zimmermann, 3Technical Development Biosimilars, Novartis Biologics Technical Development and Manufacturing, Oberhaching, Germany; and
  • Robert Fischer, 3Technical Development Biosimilars, Novartis Biologics Technical Development and Manufacturing, Oberhaching, Germany; and
  • Vera Koppenburg, 4Sandoz Biopharmaceuticals, Oberhaching, Germany; and
  • Salah-Dine Chibout, 1Discovery and Investigative Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland;
  • Timothy M. Wright, 5Novartis Pharma Development, Basel, Switzerland
  • Andreas Seidl, 3Technical Development Biosimilars, Novartis Biologics Technical Development and Manufacturing, Oberhaching, Germany; and
  • Michael Kammüller, 1Discovery and Investigative Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland;

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